Double accumulation, back to back or Duo Stim is an advanced assisted reproduction technique designed especially for patients with low ovarian reserve or who retrieve a limited number of eggs in a single stimulation cycle. Its goal is to accumulate oocytes or embryos over two (or more) consecutive cycles. This innovative approach is particularly beneficial for patients with diminished ovarian reserve, women of advanced maternal age, or those with time-sensitive fertility plans (e.g., prior to cancer treatment or before undergoing Preimplantation Genetic Testing).
Instead of performing one stimulation cycle followed by fertilization and embryo transfer, this protocol allows for two back-to-back ovarian stimulations—without waiting for a full menstrual cycle between them. Eggs retrieved from both cycles are then either vitrified or fertilized, and embryos are transferred together in a single attempt.
At Advanced Fertility Center Cancún, we carefully evaluate each case to determine whether double accumulation is the right strategy for you. Our team of medical specialists and embryologists is highly trained in designing customized protocols to maximize your chances of success—with state-of-the-art technology and compassionate care at every step of your journey.
